'Deep sequencing' gives clues to stem cell control

2019-03-08 03:07:01

WHAT makes an unspecialised cell turn into a fully functional kidney, liver or blood cell? The short answer is proteins and pieces of RNA that alter gene activity within cells. But with thousands of these “regulatory elements” to choose from, finding the relevant parts is a headache for anyone aiming to manipulate stem cells. A new technique may soon give researchers a lot more control. Piero Carninci at the RIKEN Yokohama Institute’s Omics Science Center in Japan, and colleagues,